Journal of Voice
Volume 24, Issue 5 , Pages 626-635 , September 2010

Implantation of Esterified Hyaluronic Acid in Microdissected Reinke's Space After Vocal Fold Microsurgery: Short- and Long-Term Results

Presented at the 36th Voice Foundation's Symposium: “Care of the Professional Voice,” Philadelphia, 29 May–3 June 2007.

  • Camille L. Finck

      Affiliations

    • Department of Otorhinolaryngology, University of Liège, Liège, Belgium
    • Corresponding Author InformationAddress correspondence and reprint requests to Camille L. Finck, Department of Otorhinolaryngology, CHU Sart Tilman, University of Liège, Boulevard de l'Hôpital, B-4000 Liège, Belgium.
    • ,
  • Bernard Harmegnies

      Affiliations

    • Speech Sciences Laboratory, University of Mons (Académie Universitaire Wallonie-Bruxelles), Mons, Belgium
    • ,
  • Angélique Remacle

      Affiliations

    • Department of Otorhinolaryngology, University of Liège, Liège, Belgium
    • ,
  • Philippe Lefebvre

      Affiliations

    • Department of Otorhinolaryngology, University of Liège, Liège, Belgium

Received 9 October 2008 ,Accepted 31 December 2008.

References 

  1. Ward PD, Thibeault SL, Gray SD. Hyaluronic acid: its role in voice. J Voice. 2002;16:303–309
  2. Butler JE, Hammond TH, Gray SD. Gender-related differences of hyaluronic acid distribution in the human vocal fold. Laryngoscope. 2001;111:907–911
  3. Gray SD, Titze IR, Chan R, Hammond TH. Vocal fold proteoglycans and their influence on biomechanics. Laryngoscope. 1999;109:845–854
  4. Chan RW, Gray SD, Titze IR. The importance of hyaluronic acid in vocal fold biomechanics. Otolaryngol Head Neck Surg. 2001;124:607–614
  5. Balazs EA, Larsen NE. Hyaluronan: aiming for perfect skin regeneration. In:  Garg HG editors. Scarless Wound Healing. New York: Marcel Dekker; 2000;p. 143–160
  6. Thibeault SL, Rousseau B, Welham NV, Hirano S, Bless DM. Hyaluronan levels in acute vocal fold scar. Laryngoscope. 2004;114:760–764
  7. Finck C, Lefebvre P. Implantation of esterified hyaluronic acid in microdissected Reinke's space after vocal fold microsurgery: first clinical experiences. Laryngoscope. 2005;115:1841–1847
  8. Uloza V. Effects on voice by endolaryngeal microsurgery. Eur Arch Otorhinolaryngol. 1999;256:312–315
  9. Woo P, Casper J, Colton R, Brewer D. Aerodynamic and stroboscopic findings before and after microlaryngeal phonosurgery. J Voice. 1994;8:186–194
  10. Zeitels SM, Hillman RE, Bunting GW, Vaughn T. Reinke's edema: phonatory mechanisms and management strategies. Ann Otol Rhinol Laryngol. 1997;106(7 Pt 1):533–543
  11. Chan RW, Titze IR. Viscosities of implantable biomaterials in vocal fold augmentation surgery. Laryngoscope. 1998;108:725–731
  12. Hertegård S, Hallén L, Laurent C, Lindström E, Olofsson K, Testad P, et al. Cross-linked hyaluronan versus collagen for injection treatment of glottal insufficiency: 2-year follow-up. Acta Otolaryngol. 2004;124:1208–1214
  13. Caton T, Thibeault SL, Klemuk S, Smith ME. Viscoelasticity of hyaluronan and nonhyaluronan based vocal fold injectables: implications for mucosal versus muscle use. Laryngoscope. 2007;117:516–521
  14. Chan RW, Titze IR. Hyaluronic acid (with fibronectin) as a bioimplant for the vocal fold mucosa. Laryngoscope. 1999;109(7 Pt 1):1142–1149
  15. Chan RW, Titze IR. Viscoelastic shear properties of human vocal fold mucosa: measurement methodology and empirical results. J Acoust Soc Am. 1999;106(4 Pt 1):2008–2021
  16. Klemuk SA, Titze IR. Viscoelastic properties of three vocal-fold injectable biomaterials at low audio frequencies. Laryngoscope. 2004;114:1597–1603
  17. Hallen L, Dahlqvist A, Laurent C. Dextranomeres in hyaluronan (DiHA): a promising substance in treating vocal cord insufficiency. Laryngoscope. 1998;108:393–397
  18. Hallen L, Testad P, Sederholm E, Dahlqvist A, Laurent C. DiHA (dextranomers in hyaluronan) injections for treatment of insufficient closure of the vocal folds: early clinical experiences. Laryngoscope. 2001;111:1063–1067
  19. Hertegård S, Hallén L, Laurent C, Lindström E, Olofsson K, Testad P, et al. Cross-linked hyaluronan used as augmentation substance for treatment of glottal insufficiency: safety aspects and vocal fold function. Laryngoscope. 2002;112:2211–2219
  20. Hsiung MW, Lin YS, Su WF, Lee JC, Wang HW. Fat augmentation following microsurgical removal of the vocal nodules: long-term results. ORL J Otorhinolaryngol Relat Spec. 2003;65:169–175
  21. Longaker MT, Chiu ES, Adzick NS, Stern M, Harrison MR, Stern R. Studies in fetal wound healing. V. A prolonged presence of hyaluronic acid characterizes fetal wound fluid. Ann Surg. 1991;213:292–296
  22. Huang-Lee LL, Wu JH, Nimni ME. Effects of hyaluronan on collagen fibrillar matrix contraction by fibroblasts. J Biomed Mater Res. 1994;28:123–132
  23. Rydell N. Decreased granulation tissue reaction after installment of hyaluronic acid. Acta Orthop Scand. 1970;41:307–311
  24. King SR, Hickerson WL, Proctor KG. Beneficial actions of exogenous hyaluronic acid on wound healing. Surgery. 1991;109:76–84
  25. Day AJ, Prestwich GD. Hyaluronan-binding proteins: tying up the giant. J Biol Chem. 2002;277:4585–4588
  26. Savani R, Bagli DJ, Harrisson RE, Turley EA. The role of hyaluronan receptor interactions in wound repair. In: Scarless Wound Healing. New York: Marcel Dekker; 2000;p. 115–137
  27. Wang F, Garza LA, Kang S, Varari J, Orringer JS, Fisher GJ, et al. In vivo stimulation of de novo collagen production caused by cross-linked hyaluronic acid dermal filler injections in photo-damaged human skin. Arch Dermatol. 2007;143:155–163
  28. Breuing K, Eriksson E, Liu P, Miller D. Healing of partial thickness porcine wounds in a liquid environment. J Surg Res. 1991;52:50–58
  29. Arnold F, Jia C, Cherry GW, Carbow B, Meyer-Ingold W, Bader B, et al. Hyaluronan, heterogenity and healing: the effects of ultrapure hyaluronan of defined molecular size on the repair of full-thickness pig skin wounds. Wound Repair Regen. 1995;3:299–310
  30. Andre P. Evaluation of the safety of a non-animal stabilized hyaluronic acid (NASHA – Q-Medical, Sweden) in European countries: a retrospective study from 1997 to 2001. J Eur Acad Dermatol Venereol. 2004;18:422–425

PII: S0892-1997(09)00004-6

doi: 10.1016/j.jvoice.2008.12.015

Journal of Voice
Volume 24, Issue 5 , Pages 626-635 , September 2010

Article Tools

* Image Usage & Resolution