Summary
Objectives/Hypotheses
The objective was to assess the utility of selected “resonant voice” (RV) exercises
for the reduction of acute vocal fold inflammation. The hypothesis was that relatively
large-amplitude, low-impact vocal fold exercises associated with RV would reduce inflammation
more than spontaneous speech (SS) and possibly more than voice rest.
Study Design
The study design was prospective, randomized, and double blind.
Methods
Nine vocally healthy adults underwent a 1-hour vocal loading procedure, followed by
randomization to a SS condition, vocal rest condition, or RV exercise condition. Treatments
were monitored in clinic for 4 hours and continued extraclinically until the next
morning. At baseline (BL), immediately after loading, after the 4-hour in-clinic treatment,
and 24 hours post-BL, secretions were suctioned from the vocal folds bilaterally and
submitted to enzyme-linked immunosorbent assay to estimate concentrations of key markers
of tissue injury and inflammation: interleukin (IL)-1β, IL-6, IL-8, tumor necrosis
factor α, matrix metalloproteinase (MMP)-8, and IL-10.
Results
Complete data sets were obtained for three markers—IL-1β, IL-6, and MMP-8—for one
subject in each treatment condition. For these markers, results were poorest at 24-hour
follow-up in the SS condition, sharply improved in the voice rest condition, and was
the best in the RV condition. Average results for all markers and responsive subjects
with normal BL mediator concentrations revealed an almost identical pattern.
Conclusions
Some forms of tissue mobilization may be useful to attenuate acute vocal fold inflammation.
Key Words
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Article Info
Publication History
Accepted:
March 16,
2012
Identification
Copyright
© 2012 The Voice Foundation. Published by Elsevier Inc. All rights reserved.
