Summary
Isolated laryngeal sarcoidosis is a very rare disease. In most cases, it will present
as a supraglottic pale edematous swelling. In our case, the patient presented with
hoarseness and dyspnea during exertion. Laryngeal examination did show not only supraglottic
edema but also prominent subglottic swelling and edematous true vocal folds. Histology
showed noncaseating granulomas. After excluding other causes and localizations, the
patient was diagnosed with laryngeal sarcoidosis and treated with systemic corticosteroid
with good result. We describe our case of isolated transglottic sarcoidosis and discuss
the disease, its presentation, diagnosis, and therapeutic options.
Key Words
To read this article in full you will need to make a payment
Purchase one-time access:
Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online accessOne-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:
Subscribe to Journal of VoiceAlready a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
References
- Laryngeal sarcoidosis.J Voice. 2002; 16: 283-288
- Laryngeal sarcoidosis presenting as an isolated submucosal vocal fold mass.J Voice. 1999; 13: 240-245
- Statement on sarcoidosis.Am J Respir Crit Care Med. 1999; 160: 736-755
- Treatment of laryngeal sarcoidosis with intralesional steroid injection.Ann Otol Rhinol Laryngol. 1987; 96: 713-715
- Clinically isolated laryngeal sarcoidosis.Eur Arch Otorhinolaryngol. 2011; 268: 575-580
- Laryngeal sarcoidosis: report of 13 patients.Ann Otol Rhinol Laryngol. 1982; 91: 359-362
- Laryngeal sarcoidosis causing acute upper airway obstruction.Am J Emerg Med. 2008; 26: 114.e1-114.e3
- Upper airway. 4: Sarcoidosis of the upper respiratory tract (SURT).Thorax. 2010; 65: 181-186
- Upper respiratory tract involvement of sarcoidosis in the Turkish population.Otolaryngol Head Neck Surg. 2006; 134: 848-851
- Office-based steroid injection for chronic laryngitis and glottic stenosis secondary to sarcoidosis.Laryngoscope. 2009; 119: 101
- Endoscopic airway management of laryngeal sarcoidosis.Arch Otolaryngol Head Neck Surg. 2010; 136: 251-255
- Sarcoidosis.Lancet. 2003; 361: 1111-1118
- Cytotoxic agents in the treatment of laryngeal sarcoidosis: a case report and review of the literature.J Voice. 2006; 20: 481-484
Article info
Publication history
Published online: May 20, 2013
Accepted:
March 22,
2013
Identification
Copyright
© 2013 The Voice Foundation. Published by Elsevier Inc. All rights reserved.
