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Research Article| Volume 27, ISSUE 6, P769-777, November 2013

Three-Dimensional Reconstruction of Human Vocal Folds and Standard Laryngeal Cartilages Using Computed Tomography Scan Data

Published:October 10, 2013DOI:https://doi.org/10.1016/j.jvoice.2013.06.003

      Summary

      Three-dimensional (3D) computer models of the human larynx are useful tools for research and for eventual clinical applications. Recently, computed tomography (CT) scanning and magnetic resonance imaging (MRI) have been used to recreate realistic models of human larynx. In the present study, CT images were used to create computer models of vocal folds, vocal tract, and laryngeal cartilages, and the procedure to create solid models are explained in details. Vocal fold and vocal tract 3D models of healthy and postsurgery larynges during phonation and respiration were created and morphometric parameters were quantified. The laryngeal framework of eight patients was also reconstructed from CT scan images. For each cartilage, morphometric landmarks were measured on the basis of their importance for biomechanical modeling. A quantitative comparison was made between measured values from the reconstructions and those from human excised larynges in literature. The good agreement between these measurements supports the accuracy of CT scan-based 3D models. Generic standard models of the laryngeal framework were created using known features in modeling softwares. They were created based on the morphometric landmark dimensions previously defined, preserving all biomechanically important dimensions. These models are accessible, subject independent, easy to use for computational simulations, and make the comparisons between different studies possible.

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      References

        • Tayama N.
        • Chan R.
        • Kaga K.
        • Titze I.
        Geometric characterization of the laryngeal cartilage framework for the purpose of biomechanical modeling.
        Ann Otol Rhinol laryngol. 2001; 110: 1154
        • Oyamada Y.
        • Yumoto E.
        • Nakano K.
        • Goto H.
        Asymmetry of the vocal folds in patients with vocal fold immobility.
        Arch Otolaryngol Head Neck Surg. 2005; 131: 399
        • Hiramatsu H.
        • Tokashiki R.
        • Suzuki M.
        Usefulness of three-dimensional computed tomography of the larynx for evaluation of unilateral vocal fold paralysis before and after treatment: technique and clinical applications.
        Eur Arch Otorhinolaryngol. 2008; 265: 725-730
        • Gökcan M.K.
        • Kurtulu D.F.
        • Üstüner E.
        • et al.
        A computational study on the characteristics of airflow in bilateral abductor vocal fold immobility.
        Laryngoscope. 2010; 120: 1808-1818
        • Šidlof P.
        • Švec J.
        • Horá ek J.
        • Veselý J.
        • Klepá ek I.
        • Havlík R.
        Geometry of human vocal folds and glottal channel for mathematical and biomechanical modeling of voice production.
        J Biomech. 2008; 41: 985-995
        • Eckel H.
        • Sittel C.
        • Zorowka P.
        • Jerke A.
        Dimensions of the laryngeal framework in adults.
        Surg Radiol Anat. 1994; 16: 31-36
        • Sprinzl G.M.
        • Eckel H.E.
        • Sittel C.
        • Pototschnig C.
        • Koebke J.
        Morphometric measurements of the cartilaginous larynx: an anatomic correlate of laryngeal surgery.
        Head Neck. 1999; 21: 743-750
        • Eckel H.E.
        • Sittel C.
        Morphometry of the larynx in horizontal sections.
        Am J Otolaryngol. 1995; 16: 40-48
        • Storck C.
        • Juergens P.
        • Fischer C.
        • et al.
        Biomechanics of the cricoarytenoid joint: three-dimensional imaging and vector analysis.
        J Voice. 2011; 25: 406-410
        • Chen T.
        • Chodara A.M.
        • Sprecher A.J.
        • et al.
        A new method of reconstructing the human laryngeal architecture using micro-MRI.
        J Voice. 2012; 26: 555-562
        • Mau T.
        Three-dimensional morphometric analysis of cricoarytenoid subluxation.
        J Voice. 2012; 26: 133-136
        • Selbie W.S.
        • Gewalt S.L.
        • Ludlow C.L.
        Developing an anatomical model of the human laryngeal cartilages from magnetic resonance imaging.
        J Acoust Soc Am. 2002; 112: 1077
        • Yushkevich P.A.
        • Piven J.
        • Hazlett H.C.
        • et al.
        User-guided 3D active contour segmentation of anatomical structures: significantly improved efficiency and reliability.
        Neuroimage. 2006; 31: 1116-1128
        • Mupparapu M.
        • Vuppalapati A.
        Ossification of laryngeal cartilages on lateral cephalometric radiographs.
        Angle Orthod. 2005; 75: 196-201
        • Field D.A.
        Laplacian smoothing and Delaunay triangulations.
        Commun Appl Numer Methods. 1988; 4: 709-712
        • Windisch G.
        • Hammer G.P.
        • Prodinger P.M.
        • Friedrich G.
        • Anderhuber F.
        The functional anatomy of the cricothyroid joint.
        Surg Radiol Anat. 2010; 32: 135-139
        • Joshi M.
        • Joshi S.
        • Joshi S.
        Morphometric study of cricoid cartilages in Western India.
        Australas Med J. 2010; 4: 542-547
        • Hunter E.J.
        • Titze I.R.
        Individual subject laryngeal dimensions of multiple mammalian species for biomechanical models.
        Ann Otol Rhinol Laryngol. 2005; 114: 809