Summary
Objectives
The present study was conducted to study the efficacy of intralesional steroid (ILS)
injection in small benign vocal fold lesions and compare the outcomes with microlaryngeal
surgery in terms of improvement in symptoms and reduction in lesion size.
Methods
The current randomized control trial was conducted in the Department of Otolaryngology
at the Postgraduate Institute of Medical Education and Research in Chandigarh between
2014 and 2015. The clinical diagnosis was based on appearance of the lesion during
endoscopy and the mucosal vibration pattern. Subjects with lesions of size less than
or equal to 5 mm were included.
Results
A total of 29 subjects were included in the study and 15 (nine men and six women)
of them were randomized to receive ILS injection. Fourteen (13 men and one woman)
were randomized to the second group to receive initial microlaryngeal surgery. We
noted significant reduction in the size of the lesion among subjects undergoing ILS
injection at 12 weeks (1.11 + 1.45 mm) as compared to baseline (2.63 + 1.28 mm) with
no recurrence.
Conclusions
ILSs are effective in reducing size of lesion and also improve acoustic parameters,
perceptual analysis, and grade of dysphonia in patients presenting with small benign
vocal cord lesions.
Key Words
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Article info
Publication history
Published online: August 01, 2018
Accepted:
April 12,
2018
Identification
Copyright
© 2018 The Voice Foundation. Published by Elsevier Inc. All rights reserved.
