Summary
Objectives
To reveal and to compare the voice pathologies and the detectable laryngeal findings
in different phases of rheumatoid arthritis (RA).
Study design
Prospective clinical study.
Methods
Sixty-seven consecutive patients with RA, followed up at our Physical Therapy and
Rehabilitation Clinic, were included in the study. Disease activity indices of patients
were calculated with Disease Activity Score-28 Index. With Voice Handicap Index (VHI),
patients answered 30 questions of functional, physical, and emotional aspects. Videolaryngostroboscopy
was performed by the same physician for all patients with a 70° rigid telescope (Karl
Storz, Tuttlingen, Germany), and then acoustic voice analysis (PRAAT program) was
performed. Reflux Finding Score was used in evaluating the laryngopharyngeal reflux.
Results
Posterior comissure hypertrophy (25.3%) and hyperemia/edema in arytenoid mucosa (22.3%)
were detected as the most frequent findings. Other common findings were thick endolaryngeal
mucus, vocal cord varices. Twenty-two patients had reflux findings (32.8%). Fundamental
frequency, shimmer, maximum phonation time and VHI value were not significantly different
between active and remission phases of the disease (P > 0.05). In remission phase, the jitter value and the noise to harmonic ratio value
were significantly higher (P < 0.05) than active phase of the disease (P < 0.05). Abnormal laryngeal findings are higher in active phase (28% in remission
phase, 54% in active phase). The mean VHI score of patients in remission phase was
lower than that in active phase.
Conclusion
RA should be included in the differential diagnosis of patients with voice disorders.
Nonspecific pathologies are more prevalent in the picture. There are more objective
findings and subjective complaints of patients in active phase of the disease than
in the remission phase.
Key Words
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Article info
Publication history
Published online: November 16, 2018
Accepted:
October 24,
2018
Footnotes
The authors have no funding, financial relationships, or conflicts of interest to report.
Identification
Copyright
© 2018 The Voice Foundation. Published by Elsevier Inc. All rights reserved.
