Summary
Purpose
Subthalamic nucleus deep brain stimulation (STN-DBS) parameters, for example the frequency
of stimulation, seem to affect speech and voice aspects. However, this influence is
not well understood. This study aimed to investigate the impact of low- and high-frequency
STN-DBS on voice and speech for people with Parkinson's disease.
Methods
Nineteen individuals with Parkinson's disease who received bilateral STN-DBS were
assessed for motor performance (Unified Parkinson's Disease Rating Scale-III), perceptual
evaluation of voice (grade, roughness, breathiness, asthenia, strain, and instability
[GRBASI]), dysarthria assessment, and computerized acoustic analysis of voice upon
receiving low-frequency (60 Hz) and high-frequency (130 Hz) STN-DBS.
Results
In the GRBASI protocol, asthenia, and instability were significantly better at 130
Hz of stimulation. In the dysarthria evaluation, the phonation aspect, articulation,
and grade of dysarthria showed deterioration at the same high-frequency condition.
There was no significant difference for any vocal acoustic measures.
Conclusion
The high-frequency of STN-DBS may affect speech and voice differently, leading to
an amelioration of the vocal production, but with adverse effects in the speech control.
Key Words
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Article info
Publication history
Published online: November 16, 2018
Accepted:
October 25,
2018
Identification
Copyright
© 2018 The Voice Foundation. Published by Elsevier Inc. All rights reserved.
