Summary
Objective
The objective of this observational study was to assess the relationship between established
aging biobehavioral measures and voice decline in normally aging adults.
Study design
Cross-sectional study.
Methods
Participants 60–85 years of age were divided into two age and sex-matched groups,
based on the presence or absence of presbylaryngeus. Both groups underwent a battery
of tests measuring anthropometric variables, inflammatory markers, general health
measures, and vocal function parameters. Differences from the norm were calculated
for all variables. Parametric and nonparametric tests were performed to assess group
differences. In addition, variable selection analysis was performed to determine variables
that were most influential in predicting the occurrence of presbylaryngeus in our
current sample.
Results
Fifty-three participants were divided into age and sex-matched groups of “presbylaryngeus”
(n = 26) and “non-presbylaryngeus” (n = 27). The two groups were statistically different
in select measures of inflammatory markers, general health measures, and vocal function
parameters. Anthropometric measures were not statistically different. Based on variable
selection, the variables most predictive of the presence of presbylaryngeus were measures
of the Physical Activity Scale of the Elderly, C-reactive protein, laryngeal airway
resistance, and vocal roughness.
Conclusions
In addition to group differences in vocal function measures, results for the presbylaryngeus
group consistently trended sub-optimally on anthropometric measures, two inflammatory
markers, and general health measures. These results suggest that this sample of individuals
with presbylaryngeus demonstrated greater biobehavioral deficits associated with aging
as compared to age and sex-matched non-presbylaryngeus individuals.
Level of Evidence
Key Words
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Article info
Publication history
Published online: November 29, 2018
Accepted:
November 7,
2018
Footnotes
Source of financial support: The project described was supported by the following grants; the National Center for Advancing Translational Sciences, National Institutes of Health, through grant number UL1TR000117, the National Institute on Deafness and Other Communication Disorders DC010806 to CAM and JCS; and DC11285 to CAM and the University of Kentucky, Department of Health Sciences Research Grant to JCS. The content is solely the responsibility of the authors and does not necessarily represent the official views of the NIH. http://dx.doi.org/10.13039/100006108
Conflict of interest: None
Financial disclosure: Authors VA, CAM, RA, TU, and JCS receive a salary from the University of Kentucky. Author 4 receives a salary from the University of Missouri.
Identification
Copyright
© 2018 The Voice Foundation. Published by Elsevier Inc. All rights reserved.
