Relative Fundamental Frequency in Individuals with Globus Syndrome and Muscle Tension Dysphagia

  • Daniel P. Buckley
    Correspondence
    Address correspondence and reprint requests to Daniel P. Buckley, Boston University, Department of Speech, Language, and Hearing Sciences, 677 Beacon St, MA 02215, USA.
    Affiliations
    Department of Speech, Language, and Hearing Sciences, Boston University, Boston, Massachusetts

    Department of Otolaryngology – Head and Neck Surgery, Boston University School of Medicine, Boston, Massachusetts
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  • Jennifer M. Vojtech
    Affiliations
    Department of Speech, Language, and Hearing Sciences, Boston University, Boston, Massachusetts

    Department of Biomedical Engineering, Boston University, Boston, Massachusetts

    Delsys, Inc., Natick, Massachusetts

    Altec, Inc., Natick, Massachusetts
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  • Cara E. Stepp
    Affiliations
    Department of Speech, Language, and Hearing Sciences, Boston University, Boston, Massachusetts

    Department of Biomedical Engineering, Boston University, Boston, Massachusetts
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Published:November 23, 2021DOI:https://doi.org/10.1016/j.jvoice.2021.10.013

      Summary

      Objective

      Relative fundamental frequency (RFF) has been investigated as an acoustic measure to assess for changes in laryngeal tension. This study aimed to assess RFF in individuals with globus syndrome, individuals with muscle tension dysphagia (MTDg), and individuals with typical voices.

      Methods

      RFF values were calculated from the speech acoustics of individuals with globus syndrome (n = 12), individuals with MTDg (n = 12), and age- and sex-matched controls with typical voices (n = 24). An analysis of variance was performed on RFF values to assess the effect of group.

      Results

      There was no statistically significant effect of group on RFF values, with similar values for individuals with globus syndrome, individuals with MTDg, and control participants.

      Conclusions

      These results suggest that individuals with these disorders do not appear to possess paralaryngeal muscle tension in a locus and/or manner that directly impacts voice production.

      Keywords

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      REFERENCES

        • Kang C.H.
        • Hentz J.G.
        • Lott D.G.
        Muscle tension dysphagia: symptomology and theoretical framework.
        Otolaryngol Head Neck Surg. 2016; 155: 837-842https://doi.org/10.1177/0194599816657013
        • Kortequee S.
        • Karkos P.D.
        • Atkinson H.
        • et al.
        Management of globus pharyngeus.
        Int J Otolaryngol. 2013; 2013946780https://doi.org/10.1155/2013/946780
        • Wareing M.
        • Elias A.
        • Mitchell D.
        Management of globus sensation by the speech therapist.
        Logoped Phoniatr Vocol. 1997; 22: 39-42
        • Kang C.H.
        • Zhang N.
        • Lott D.G.
        Muscle tension dysphagia: contributing factors and treatment efficacy.
        Ann Otol Rhinol Laryngol. 2020; 3489420966339https://doi.org/10.1177/0003489420966339
        • Oates J.
        • Winkworth A.
        Current knowledge, controversies and future directions in hyperfunctional voice disorders.
        Int J Speech Lang Pathol. 2008; 10: 267-277https://doi.org/10.1080/17549500802140153
        • Lee B.E.
        • Kim G.H.
        Globus pharyngeus: a review of its etiology, diagnosis and treatment.
        World J Gastroenterol. 2012; 18: 2462-2471https://doi.org/10.3748/wjg.v18.i20.2462
        • Hill J.
        • Stuart R.C.
        • Fung H.K.
        • et al.
        Gastroesophageal reflux, motility disorders, and psychological profiles in the etiology of globus pharyngis.
        Laryngoscope. 1997; 107: 1373-1377https://doi.org/10.1097/00005537-199710000-00015
        • Chevalier J.M.
        • Brossard E.
        • Monnier P.
        Globus sensation and gastroesophageal reflux.
        Eur Arch Otorhinolaryngol. 2003; 260: 273-276https://doi.org/10.1007/s00405-002-0544-0
        • Morrison M.
        • Rammage L.
        • Emami A.J.
        The irritable larynx syndrome.
        J Voice. 1999; 13: 447-455https://doi.org/10.1016/s0892-1997(99)80049-6
        • Ding H.
        • Duan Z.
        • Yang D.
        • et al.
        High-resolution manometry in patients with and without globus pharyngeus and/or symptoms of laryngopharyngeal reflux.
        BMC Gastroenterol. 2017; 17: 109https://doi.org/10.1186/s12876-017-0666-x
        • Khalil H.B.
        • Hilton-Pierce, M MW
        • Vincent J
        The use of speech therapy in the treatment of globus pharyngeus patients. A randomised controlled trial.
        Revue de Laryngologie - Otologie - Rhinologie. 2002; 124: 187-190
        • Cheol M.A.
        The efficacy of voice therapy in globus pharyngeus.
        Korean J Otorhinolaryngol-Head Neck Surg. 1998; 41: 246-250
        • Drossman D.A.
        • Dumitrascu D.L.
        Rome III: New standard for functional gastrointestinal disorders.
        J Gastrointestin Liver Dis. 2006; 15: 237-241
        • Drossman D.A.
        The functional gastrointestinal disorders and the Rome III process.
        Gastroenterology. 2006; 130: 1377-1390https://doi.org/10.1053/j.gastro.2006.03.008
        • Drossman D.A.
        Functional gastrointestinal disorders: history, pathophysiology, clinical features and rome IV.
        Gastroenterology. 2016; https://doi.org/10.1053/j.gastro.2016.02.032
        • Aziz Q.
        • Fass R.
        • Gyawali C.P.
        • et al.
        Functional Esophageal Disorders.
        Gastroenterology. 2016; https://doi.org/10.1053/j.gastro.2016.02.012
        • Kuribayashi S.
        • Kusano M.
        • Kawamura O.
        • et al.
        [Functional gastrointestinal disorders(FGID): progress in diagnosis and treatments. Topic II. Current status and future prospective of medical care of the representative disorders; 1. Functional esophageal disorders (chest pain or functional dysphagia)].
        Nihon Naika Gakkai Zasshi. 2013; 102: 46-54https://doi.org/10.2169/naika.102.46
        • Hamdan A.L.
        • Ziade G.
        • Khalifee E.
        • et al.
        Prevalence of MTD among patients with functional dysphagia.
        OTO Open. 2018; 22473974X18792469https://doi.org/10.1177/2473974X18792469
        • Patel D.
        • Kavitt Robert T
        • Vaezi Michael F.
        Evaluation and Management of Dysphagia An Evidence-Based Approach.
        1st ed. Springer International Publishing, 2020
        • Krasnodebska P.
        • Jarzynska-Bucko A.
        • Szkielkowska A.
        • et al.
        Clinical and electromyographic assessment of swallowing in individuals with functional dysphonia associated with dysphagia due to muscle tension or atypical swallowing.
        Audiol Res. 2021; 11: 167-178https://doi.org/10.3390/audiolres11020015
        • DePietro J.D.
        • Rubin S.
        • Stein D.J.
        • et al.
        Laryngeal manipulation for dysphagia with muscle tension dysphonia.
        Dysphagia. 2018; 33: 468-473https://doi.org/10.1007/s00455-018-9875-x
        • Behrman A.
        • Dahl L.D.
        • Abramson A.L.
        • et al.
        Anterior-posterior and medial compression of the supraglottis: signs of nonorganic dysphonia or normal postures?.
        J Voice. 2003; 17: 403-410https://doi.org/10.1067/s0892-1997(03)00018-3
        • Garaycochea O.
        • Navarrete J.M.A.
        • del Rio B.
        • et al.
        Muscle tension dysphonia: which laryngoscopic features can we rely on for diagnosis?.
        J Voice. 2019; 33https://doi.org/10.1016/j.jvoice.2018.04.015
        • Morrison M.D.
        • Rammage L.A.
        Muscle Misuse voice disorders - description and classification.
        Acta Oto-Laryngologica. 1993; 113: 428-434https://doi.org/10.3109/00016489309135839
        • Stager S.V.
        • Bielamowicz S.A.
        • Regnell J.R.
        • et al.
        Supraglottic activity: evidence of vocal hyperfunction or laryngeal articulation?.
        J Speech Lang Hear Res. 2000; 43: 229-238https://doi.org/10.1044/jslhr.4301.229
        • Fernandez S.
        • Garaycochea O.
        • Martinez-Arellano A.
        • et al.
        Does more compression mean more pressure? a new classification for muscle tension dysphonia.
        J Speech Lang Hear Res. 2020; 63: 2177-2184https://doi.org/10.1044/2020_JSLHR-20-00042
        • Stepp C.E.
        • Sawin D.E.
        • Eadie T.L.
        The relationship between perception of vocal effort and relative fundamental frequency during voicing offset and onset.
        J Speech Lang Hear Res. 2012; 55: 1887-1896https://doi.org/10.1044/1092-4388(2012/11-0294)
        • Lien Y.A.
        • Michener C.M.
        • Eadie T.L.
        • et al.
        Individual monitoring of vocal effort with relative fundamental frequency: relationships with aerodynamics and listener perception.
        J Speech Lang Hear Res. 2015; 58: 566-575https://doi.org/10.1044/2015_JSLHR-S-14-0194
        • Stepp C.E.
        • Hillman R.E.
        • Heaton J.T.
        The impact of vocal hyperfunction on relative fundamental frequency during voicing offset and onset.
        J Speech Lang Hear Res. 2010; 53: 1220-1226https://doi.org/10.1044/1092-4388(2010/09-0234)
        • Roy N.
        • Fetrow R.A.
        • Merrill R.M.
        • et al.
        Exploring the clinical utility of relative fundamental frequency as an objective measure of vocal hyperfunction.
        J Speech Lang Hear Res. 2016; 59: 1002-1017https://doi.org/10.1044/2016_JSLHR-S-15-0354
        • Heller Murray E.S.
        • Lien Y.S.
        • Van Stan J.H.
        • et al.
        Relative fundamental frequency distinguishes between phonotraumatic and non-phonotraumatic vocal hyperfunction.
        J Speech Lang Hear Res. 2017; 60: 1507-1515https://doi.org/10.1044/2016_JSLHR-S-16-0262
        • Stepp C.E.
        Relative fundamental frequency during vocal onset and offset in older speakers with and without Parkinson's disease.
        J Acoust Soc Am. 2013; 133: 1637-1643https://doi.org/10.1121/1.4776207
        • Goberman A.M.
        • Blomgren M.
        Fundamental frequency change during offset and onset of voicing in individuals with Parkinson disease.
        J Voice. 2008; 22: 178-191https://doi.org/10.1016/j.jvoice.2006.07.006
        • Buckley D.P.
        • Cadiz M.D.
        • Eadie T.L.
        • et al.
        Acoustic model of perceived overall severity of dysphonia in adductor-type laryngeal dystonia.
        J Speech Lang Hear Res. 2020; 63: 2713-2722https://doi.org/10.1044/2020_JSLHR-19-00354
        • Eadie T.L.
        • Stepp C.E.
        Acoustic correlate of vocal effort in spasmodic dysphonia.
        Ann Otol Rhinol Laryngol. 2013; 122: 169-176https://doi.org/10.1177/000348941312200305
        • Stepp C.E.
        • Merchant G.R.
        • Heaton J.T.
        • et al.
        Effects of voice therapy on relative fundamental frequency during voicing offset and onset in patients with vocal hyperfunction.
        J Speech Lang Hear Res. 2011; 54: 1260-1266https://doi.org/10.1044/1092-4388(2011/10-0274)
        • Lien Y.A.
        • Gattuccio C.I.
        • Stepp C.E.
        Effects of phonetic context on relative fundamental frequency.
        J Speech Lang Hear Res. 2014; 57: 1259-1267https://doi.org/10.1044/2014_JSLHR-S-13-0158
        • Vojtech J.M.
        • Segina R.K.
        • Buckley D.P.
        • et al.
        Refining algorithmic estimation of relative fundamental frequency: Accounting for sample characteristics and fundamental frequency estimation method.
        J Acoust Soc Am. 2019; 146: 3184https://doi.org/10.1121/1.5131025
        • Witte R.S.
        • Witte J.S.
        Statistics.
        J. Wiley & Sons, Hoboken, NJ2010
        • Sataloff R.T.
        • Heman-Ackah Y.D.
        • Hawkshaw M.J.
        Clinical anatomy and physiology of the voice.
        Otolaryngol Clin North Am. 2007; 40 (v.): 909-929https://doi.org/10.1016/j.otc.2007.05.002
        • Pearson Jr., W.G.
        • Hindson D.F.
        • Langmore S.E.
        • et al.
        Evaluating swallowing muscles essential for hyolaryngeal elevation by using muscle functional magnetic resonance imaging.
        Int J Radiat Oncol Biol Phys. 2013; 85: 735-740https://doi.org/10.1016/j.ijrobp.2012.07.2370
        • Scoppa F.
        • Saccomanno S.
        • Bianco G.
        • et al.
        Tongue posture, tongue movements, swallowing, and cerebral areas activation: a functional magnetic resonance imaging study.
        Applied Sciences-Basel. 2020; 10 (doi:ARTN 6027 10.3390/app10176027)
        • Sasegbon A.
        • Hamdy S.
        The anatomy and physiology of normal and abnormal swallowing in oropharyngeal dysphagia.
        Neurogastroenterol Motil. 2017; 29 (doi:10.1111/nmo.13100)