Summary
Objectives
To characterize the presence and severity of anxiety and depression in patients with
symptomatic idiopathic subglottic stenosis (ISGS). To determine the relationship between
dyspnea severity and anxiety and depression symptom severity.
Methods
Patients diagnosed with idiopathic subglottic stenosis and treated at Mayo Clinic
Florida or Mayo Clinic Arizona retrospectively completed the PROMIS Depression, PROMIS
Anxiety, PROMIS Dyspnea Functional Limitations, and Dyspnea Index questionnaires.
Patients with dyspnea and without idiopathic subglottic stenosis were also asked to
complete the questionnaires as a control group.
Results
This explorative retrospective study includes 44 control patients and 46 ISGS patients.
Unadjusted and adjusted group comparisons found no statistically significant difference
in dyspnea index, depression, anxiety, nor dyspnea functional limitation scores. Relationships
between dyspnea severity and anxiety and depression severity were significant and
persistent in both groups. Anxiety and depression were positively correlated (r = 0.66). Dyspnea severity positively correlate with both anxiety and depression (anxiety
r = 0.49, depression r = 0.32).
Conclusions
Patients with symptomatic idiopathic subglottic stenosis are not at an increased risk
of having anxiety and depression when compared to other dyspneic patients. As dyspnea
severity worsens, patients are more likely to experience anxiety and depression. These
findings support the prior literature and suggest the presence of dyspnea may warrant
appropriate psychological screening and treatment to optimize dyspneic patients’ quality
of life and symptom improvement.
Key Words
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Article info
Publication history
Published online: March 26, 2022
Accepted:
February 20,
2022
Publication stage
In Press Corrected ProofFootnotes
Funding Source: None
Identification
Copyright
Published by Elsevier Inc. on behalf of The Voice Foundation.
