SUMMARY
Background
Voice outcome after carbon dioxide transoral laser microsurgery (CO2TOLMS) for glottic cancer is of prime importance. However, a comprehensive overview
according to the European Laryngological Society (ELS) classification of cordectomies
is still lacking. The aim of this systematic review is to summarize data on voice
outcome associated with individual types of ELS glottic cordectomy after CO2TOLMS.
Materials and Methods
A systematic review of the literature was performed following the Preferred Reporting
Items for Systematic Reviews and Meta-Analyses (PRISMA) Statement. The initial search
identified 936 records of which 25 publications were then included. Voice outcome
data (Voice Handicap Index [VHI] version 30, grade of dysphonia [G] and maximum phonation
time [MPT]) were extracted per resection type. Weighted averages were calculated.
Results
Data show a gradual increase in the VHI scores although they were still similar for
all cordectomy types (range 14.2 to 21.5). The grade of dysphonia showed a gradual
increase with increasing resection depth (range 1.0 to 1.9). There was a gradual decrease
in the MPT (range 15.2 to 7.2).
Conclusion
Voice outcome is related to cordectomy type with mild dysphonia characterizing ELS
type I, II and III cordectomies, while more extended cordectomies (ELS type IV, V
and VI) result in moderate dysphonia and shortness of breath during phonation. The
voice handicap experienced by patients is limited even in the more extended cordectomies
Key Words
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Article info
Publication history
Published online: April 12, 2022
Accepted:
March 6,
2022
Publication stage
In Press Corrected ProofIdentification
Copyright
© 2022 Published by Elsevier Inc. on behalf of The Voice Foundation.
