Summary
Objectives
Pulmonary function is closely associated with voice quality especially in patients
with voice disorder including unilateral vocal fold paralysis (UVFP). Injection laryngoplasty
(IL) is the standard treatment for patients with UVFP. We investigated the subjective
and objective voice outcomes according to pulmonary function test (PFT) before IL
in patients with UVFP.
Method
We retrospectively analyzed the patients who underwent IL for UVFP between 2004 and
2021 (N = 1201), and finally investigated 261 patients with PFT results before IL. The patients
were classified into three groups according to results of PFT: normal (n = 189, 72%), mild (n = 40, 15%), and moderate (n = 32, 13%) obstructive pattern. Aspiration symptoms and subjective and objective voice
parameters of voice handicap index (VHI), GRBAS score, maximal phonation time (MPT),
Jitter, Shimmer, and noise to harmonic ratio (NHR) were compared between normal and
abnormal (mild or moderate obstructive pattern) PFT groups.
Results
Age (68.0 ± 9.1 and 61.2 ± 12.6, respectively) was significantly higher and males
were more common (84.7% and 57.7%, respectively) in abnormal PFT than in normal PFT.
Aspiration showed significant improvement in all groups. The subjective and objective
voice parameters significantly improved after IL in normal and mild obstruction groups,
but MPT, Shimmer, and VHI did not significantly improve in the moderate obstruction
group. The improvement in VHI-30 after IL was significantly higher in the normal group
(20.0 ± 29.5) than in the mild (10.3 ± 32.8) or moderate (9.9 ± 33.2) obstruction
group (P = 0.035). Improved amounts of MPT, Jitter, Shimmer, and NHR were not significantly different
among the groups, but improvement of VHI was smallest in the moderate obstructive
pattern group.
Conclusion
Voice parameters showed significant improvement after IL in both normal and mild obstructive
pattern groups, but MPT and VHI did not significantly improve in the moderate obstructive
pattern group. In addition, patients with normal pulmonary function had marked improvement
of subjective symptoms after IL in comparison with patients with abnormal pulmonary
function.
Key Words
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Article info
Publication history
Published online: September 19, 2022
Accepted:
June 14,
2022
Publication stage
In Press Corrected ProofIdentification
Copyright
© 2022 Published by Elsevier Inc. on behalf of The Voice Foundation.
