Summary
Objectives
To investigate the prevalence of laryngopharyngeal reflux (LPR) and knowledge of LPR
in the Chinese nurse population.
Method
From October 2021 through December 2021, participants were recruited from the PLA
General Hospital's Sixth Medical Center. All included participants completed the Reflux
Symptom Index (RSI), and LPR was defined as RSI > 13. In addition, each participant
was asked to record whether they had any habits such as preferring to consume high-fat
food and carbonated beverages, over-eating at dinner, sedentary after meals and lying
down within 2 hour after meals, as well as whether they were aware of LPR. For the
participants with RSI >13 points, they were treated using diet and lifestyle behavioral
recommendations and were prescribed a twice daily pantoprazole (20 mg, 3 months).
Results
A total of 828 participants were included. The positivity and awareness rates of LPR
were 3.38% and 55.96%, respectively. RSI scores were significantly higher in LPR-positive
subjects than in LPR-negative (16.79 ± 4.43 vs. 1.33 ± 2.33). Among the participants
with LPR, there were significant positive association between RSI scores and preferring
to consume high-fat food and carbonated beverages, over-eating at dinner, lying down
within 2 hour after a meal, and sedentary after meals. RSI scores in 63% of participants
with LPR significantly decreased from baseline to 1 month posttreatment. From 1 to
3 months posttreatment, 90% of participants had significantly lower RSI scores than
pretreatment.
Conclusions
There are a certain number of LPR patients in the Chinese nurse population, however,
knowledge of LPR among nurses is unsatisfactory. Over-eating at dinner, lying down
within 2 hour after a meal and sedentary after meals are risk factors for LPR. With
combined regular dietary and lifestyle behavioral change and acid-suppressing treatment,
most patients with LPR achieve effective remission.
Key Words
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Article info
Publication history
Published online: July 24, 2022
Accepted:
June 23,
2022
Publication stage
In Press Corrected ProofIdentification
Copyright
© 2022 The Voice Foundation. Published by Elsevier Inc. All rights reserved.
