Summary
Purpose
This study was performed to introduce a modified procedure involving a combination
of bilateral vocal fold mucosal flaps and microsurgical sutures for the management
of anterior glottic webs and to study its efficacy in decreasing the recurrence rate
and improving voice quality.
Methods
We retrospectively reviewed 102 patients with anterior glottic webs who underwent
surgical treatment by a carbon dioxide laser incision with or without microsurgical
suturing in our hospital from May 2014 to April 2021. We focused on the reoperation
rate and the voice outcomes based on the 30-item Voice Handicap Index.
Results
This study included 102 patients with anterior glottic webs, which were caused by
papilloma excision and endoscopic laryngocarcinoma resection in 97 (95.1%) of the
102 patients; less common causes were infection and traumatic injury. All incisions
were performed along the midline with a carbon dioxide laser under microscopy and
a self-retaining laryngoscope; 37 (36.3%) patients underwent microsurgical suturing
and 65 (63.7%) patients did not. The microsuture group had a lower reoperation rate
(χ2 = 7.069, P = 0.0078) and higher voice quality (t = 2.054, P = 0.0462) than the non-microsuture group.
Conclusions
We introduced a modified procedure that can both decrease the recurrence rate and
improve the voice quality in patients with anterior glottic webs. Hence, this combination
therapy involving bilateral vocal fold mucosal flaps and microsurgical sutures is
worthy of clinical application and promotion.
Key Words
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REFERENCES
- Bilateral vocal fold granuloma and anterior glottic web after papilloma excision.Ear Nose Throat J. 2021; 5: 1-2https://doi.org/10.1177/01455613211012112
- Endoscopic management of congenital anterior glottic stenosis.Int J Pediatr Otorhinolsaryngol. 2015; 79: 2056-2058https://doi.org/10.1016/j.ijporl.2015.09.013
- The anterior laryngeal webs.Otolaryngol Clin North Am. 2008; 41: 877-888https://doi.org/10.1016/j.otc.2008.04.008
- Surgical treatment modalities for iatrogenic anterior glottic stenosis.Ann Otol Rhinol Laryngol. 2018; 127: 946-952https://doi.org/10.1177/0003489418803651
- The Voice Handicap Index (VHI): development and validation.Am J Speech Lang Pathol. 1997; 6: 66-70
- Preoperative assessment and classification of benign laryngotracheal stenosis: a consensus paper of the European Laryngological Society.Eur Arch Otorhinolaryngol. 2015; 272: 2885-2896https://doi.org/10.1007/s00405-015-3635-4
- Anterior glottic webs.Oper Techniques OtolaryngolHeadNeck Surg. 2012; 23: 111-116https://doi.org/10.1016/j.otot.2011.12.001
- Surgical management of acquired anterior glottic web: a systematic review.J Laryngol Otol. 2019; 133: 867-874https://doi.org/10.1017/S0022215119001920
- Acquired glottic stenosis—the ongoing challenge: a review of etiology, pathogenesis, and surgical management.J Voice. 2015; 29: 641-646https://doi.org/10.1016/j.jvoice.2014.10.012
- Transoral management of adult benign laryngeal stenosis.Eur Arch Otorhinolaryngol. 2021; 278: 149-158https://doi.org/10.1007/s00405-020-06210-5
- Congenital glottic web: management and anatomical observation.Clin Respir J. 2010; 4: 202-207https://doi.org/10.1111/j.1752-699X.2009.00176.x
- Can topical mitomycin prevent laryngotracheal stenosis?.Laryngoscope. 1999; 109: 1594-1600https://doi.org/10.1097/00005537-199910000-00009
- A randomized controlled trial of adjuvant mitomycin-c in endoscopic surgery for laryngotracheal stenosis.Laryngoscope. 2020; 130: 706-711https://doi.org/10.1002/lary.28025
- Antifibrotic effect of mitomycin-C on human vocal cord fibroblasts.Laryngoscope. 2019; 129: E255-E262https://doi.org/10.1002/lary.27657
- Topical use of MMC in the upper aerodigestive tract: a review on the side effects.Eur Arch Otorhinolaryngol. 2010; 267: 327-334https://doi.org/10.1007/s00405-009-1151-0
- Laryngeal cancer after topical mitomycin C application.J Laryngol Otol. 2006; 120: 1075-1076https://doi.org/10.1017/S0022215106003008
- Surgical management of anterior glottic webs.Front Pediatr. 2020; 8: 1-6https://doi.org/10.3389/fped.2020.555040
- [Surgical correction of vocal cord synechia (author's transl)].HNO. 1977; 25: 65-66
- Surgical correction of anterior web of the larynx.Laryngoscope. 1950; 60: 264-272https://doi.org/10.1288/00005537-195003000-00004
- Endoscopic laser repair of posterior glottic, subglottic and tracheal stenosis by division or micro-trapdoor flap.Laryngoscope. 1984; 94: 445-450https://doi.org/10.1288/00005537-198404000-00001
- Endoscopic Teflon keel for anterior glottic web.Ann Otol Rhinol Laryngol. 1979; 88: 467-473https://doi.org/10.1177/000348947908800404
- Web thickness determines the therapeutic effect of endoscopic keel placement on anterior glottic web.Eur Arch Otorhinolaryngol. 2017; 274: 3697-3702https://doi.org/10.1007/s00405-017-4689-2
- Vocal cord mucosal flap for the treatment of acquired anterior laryngeal web.Chin Med J (Engl). 2014; 127: 1294-1297https://doi.org/10.3760/cma.j.issn.0366-6999.20132832
- Endoscopic mucosal suturing of vocal fold with placement of stent for the treatment of glottic stenoses.Head Neck. 2010; 31: 732-737https://doi.org/10.1002/hed.21024
- Endoscopic treatment of anterior glottic webs according to Lichtenberger technique and results on 18 patients.Eur Arch Otorhinolaryngol. 2012; 269: 2075-2080https://doi.org/10.1007/s00405-012-2001-z
- Endoscopic laser anterior commissurotomy for anterior glottic web: one-stage procedure.Ann Otol Rhinol Laryngol. 2010; 119: 297-303https://doi.org/10.1177/000348941011900505
- New surgical technique for endoscopic management of anterior glottic web.B-ENT. 2010; 6: 261-264
- New keel fixing technique for endoscopic repair of anterior commissure webs.Laryngoscope. 1994; 104: 771-774https://doi.org/10.1288/00005537-199406000-00023
- Outpatient transoral laser vaporization of anterior glottic webs and keel placement: risks of airway compromise.J Voice. 1998; 12: 536-539https://doi.org/10.1016/s0892-1997(98)80062-3
- Endoscopic keel placement to treat and prevent anterior glottic webs.Ann Otol Rhinol Laryngol. 2013; 122: 672-678https://doi.org/10.1177/000348941312201102
- Single-stage, stentless endoscopic repair of anterior glottic webs.Laryngoscope. 2002; 112: 933-935https://doi.org/10.1097/00005537-200205000-00029
Article info
Publication history
Published online: September 17, 2022
Accepted:
August 11,
2022
Publication stage
In Press Corrected ProofFootnotes
This study was supported by the National Key R&D Program of China (2020YFC1316903); National Natural Science Foundation of China (81972528); 5010 Clinical Research Program of Sun Yat-sen University (2017004); China Postdoctoral Science Foundation (2021M703712).
Identification
Copyright
© 2022 The Voice Foundation. Published by Elsevier Inc. All rights reserved.