Summary
Objective
Cannabidiol (CBD) is an active ingredient in marijuana that has demonstrated anti-inflammatory
properties. It's therapeutic potential and accessibility has made the product popular.
Over the counter products (OTC) products have also demonstrated therapeutic potential
and have been accessible in public markets for a long time. The objective was to better
understand the use of CBD and OTC products amongst singers with varying singing styles.
Methods
An anonymous online survey was distributed to 1053 singers via The Research Electronic
Data Capture (RED-Cap) program in association with Drexel University. The survey aimed
to obtain information regarding singing proficiency, styles, if respondents used CBD/OTC
products, reasons for use, perceived effects on the voice due to use of these products,
and how informed were they in regards to use of these products.
Results
From 1053 singers, we obtained 144 respondents (response rate of 13.7%). The average
age of respondents was 51.8 years; There were 47 males, 93 females, and four who were
nonbinary or preferred not to provide their gender. The majority of respondents (63.2%)
were professional singers. Primary singing styles included operatic (18.1%), sacred
(20.8%), and musical theater (20.1%). Eighty-seven point five percent of respondents
reported warming up before singing and 22.9% reported cooling down after singing.
Thirteen respondents reported use of a cannabidiol (CBD) product. Information resources
for CBD used primarily came from an online website (38.5%). Among the 13 respondents
who reported use of CBD products, 46.2% of these respondents did not notice any positive
effects and 46.2% reported no negative effects on the voice when using CBD products.
Eighty-two respondents (56.9%) reported use of an OTC, supplement, or alternative
medicine product. Majority received Information resources from a physician or other
healthcare provider (81.7%). The most frequently reported OTC or complimentary medications
used were reflux medications, antihistamines, acetaminophen, and NSAIDs. Reduced inflammation,
improved voice recovery, improved voice quality, and improved voice endurance were
commonly reported positive effects on the voice with OTC/AM use. Vocal strain, hoarseness,
and dryness were the most commonly reported negative effects on the voice with OTC/AM
use.
Conclusions
Stress, anxiety, or chronic pain was often the primary reason for CBD use amongst
singers. The most common OTC medications were used reflux medications, antihistamines,
acetaminophen, and NSAIDs.
Key words
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References
- Vocal hygiene for the voice professional.Curr Opin Otolaryngol Head Neck Surg. 2009; 17: 149-154https://doi.org/10.1097/MOO.0b013e32832af105
Calcinoni O, Borgonovo G, Cassanelli A, et al. Herbs for voice database: developing a rational approach to the study of herbal remedies used in voice care. J Voice. Published online 2020. doi:10.1016/j.jvoice.2019.12.027
- The REDCap consortium: Building an international community of software platform partners.J Biomed Inform. 2019; : 95https://doi.org/10.1016/j.jbi.2019.103208
- Research electronic data capture (REDCap)-A metadata-driven methodology and workflow process for providing translational research informatics support.J Biomed Inform. 2009; 42: 377-381https://doi.org/10.1016/j.jbi.2008.08.010
- The medicinal use of cannabis and cannabinoids-An International Cross-Sectional Survey on Administration Forms.J Psychoactive Drugs. 2013; 45: 199-210https://doi.org/10.1080/02791072.2013.805976
CANNABIDIOL (CBD) Critical Review Report. Expert Committee on Drug Dependence Fortieth Meeting. World Health Organization. Geneva. June 4-7, 2018.
- The trouble with CBD oil.Med Cannabis Cannabinoids. 2018; 1: 65-72https://doi.org/10.1159/000489287
- Cannabidiol is a negative allosteric modulator of the cannabinoid CB 1 receptor.Br J Pharmacol. 2015; 172: 4790-4805https://doi.org/10.1111/bph.13250
- Cannabinoid receptor type-2 stimulation, blockade, and deletion alter the vascular inflammatory responses to traumatic brain injury.J Neuroinflammation. 2014; 11: 191https://doi.org/10.1186/s12974-014-0191-6
- Mechanisms of cannabidiol neuroprotection in hypoxic-ischemic newborn pigs: Role of 5HT1A and CB2 receptors.Neuropharmacology. 2013; 71: 282-291https://doi.org/10.1016/j.neuropharm.2013.03.027
- The profile of immune modulation by cannabidiol (CBD) involves deregulation of nuclear factor of activated T cells (NFAT).Biochem Pharmacol. 2008; 76: 726-737https://doi.org/10.1016/j.bcp.2008.06.022
- Cannabidiol and (-)Δ9-tetrahydrocannabinol are neuroprotective antioxidants.Proc Natl Acad Sci U S A. 1998; 95: 8268-8273https://doi.org/10.1073/pnas.95.14.8268
- Oral cannabidiol does not alter the subjective, reinforcing or cardiovascular effects of smoked cannabis.Neuropsychopharmacology. 2016; 41: 1974-1982https://doi.org/10.1038/npp.2015.367
- Oral cannabidiol does not produce a signal for abuse liability in frequent marijuana smokers.Drug Alcohol Depend. 2017; 172: 9-13https://doi.org/10.1016/j.drugalcdep.2016.11.030
- Performance anxiety in professional musicians: a systematic review on prevalence, risk factors and clinical treatment effects.Psychol Med. 2019; 49: 2287-2306https://doi.org/10.1017/S0033291719001910
- Effects of intra-prelimbic prefrontal cortex injection of cannabidiol on anxiety-like behavior: Involvement of 5HT1A receptors and previous stressful experience.Eur Neuropsychopharmacol. 2014; 24: 410-419https://doi.org/10.1016/j.euroneuro.2013.10.012
- The effects of cannabidiol on persecutory ideation and anxiety in a high trait paranoid group.J Psychopharmacol. 2018; 32: 276-282https://doi.org/10.1177/0269881117737400
- Medications and the voice.in: Sataloff RT Professional Voice: The Science and art of Clinical Care. fourth ed. Plural Publishing, Inc, San Diego, CA2017: 1103-1133
- Side effects of medications in professional opera singers’ voice: survey findings.Int J Otorhinolaryngol Head Neck Surg. 2020; 6: 213https://doi.org/10.18203/issn.2454-5929.ijohns20200131
Calcinoni O, Borgonovo G, Cassanelli A, et al. Herbs for voice database: developing a rational approach to the study of herbal remedies used in voice care. J Voice. Published online 2020. doi:10.1016/j.jvoice.2019.12.027
- The impact of vocal and laryngeal pathologies among professional singers: A meta-analysis.J Voice. 2018; 33: 58-65https://doi.org/10.1016/j.jvoice.2017.09.002
- Differential modulation of ROS signals and other mitochondrial parameters by the antioxidants MitoQ, resveratrol and curcumin in human adipocytes.J Recept Signal Transduct. 2013; 33: 304-312https://doi.org/10.3109/10799893.2013.822887
- "Alternative medical therapy” use among singers: prevalence and implications for the medical care of the singer.J Voice. 2000; 14: 398-409https://doi.org/10.1016/S0892-1997(00)80085-5
(PDF) Contribution of Herbal Products In Global Market. Available at: https://www.researchgate.net/publication/320357308_Contribution_of_Herbal_Products_In_Global_Market. Accessed June 22, 2021.
- Response rates and nonresponse errors in surveys.JAMA - J Am Med Assoc. 2012; 307: 1805-1806https://doi.org/10.1001/jama.2012.3532
Article info
Publication history
Published online: October 18, 2022
Accepted:
August 17,
2022
Publication stage
In Press Corrected ProofIdentification
Copyright
© 2022 The Voice Foundation. Published by Elsevier Inc. All rights reserved.
