SUMMARY
Objectives
To analyze voice outcomes and lesion regression in patients with vocal fold polyps
treated in-office using lasers.
Study design
Systematic review and meta-analysis.
Methods
The search was performed in the Medline, Embase, and Cochrane databases using the
preferred reporting items for systematic review and meta-analyses framework. There
were no limitations to the year of publication and the search included studies looking
at voice outcomes and lesion evolution of in-office laser treatment for vocal fold
polyps measured through voice-handicap index, GRB, acoustic analysis or aerodynamics
measures. Risk of bias was assessed using Cochrane's ROBINS-I tool for observational
studies. Data analysis was performed SPSS software with a significance level of 5%.
Results
We identified 167 articles, 10 of which met the inclusion criteria and were analyzed.
The total number of participants was 242. Meta-analysis showed significant improvement
in voice handicap index-10 scores (95% CI, [0.86; 1.45]) and decrease in GRB score
(95% CI, [1.09; 4.13]) after in-office laser therapy. It also showed significant improvement
in percent shimmer (95% CI, [0.26; 1.01]), and significant increase in maximum phonation
time (95% CI, [-0.92; -0.18]).
Conclusions
Laser therapy an outpatient office setting is a reliable alternative to classical
phono-microsurgery. Results show Office-based laser therapy of vocal fold polyps results
in a significant improvement in subjective voice outcomes measures. This subjective
improvement in voice quality is associated with partial or complete disease regression
on laryngeal examination and an increase in maximum phonation time. Ovlaryngeal examination
in patients with polyps treated with in-office laser.
KEY WORDS
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Article info
Publication history
Published online: March 30, 2023
Accepted:
March 2,
2023
Publication stage
In Press Corrected ProofIdentification
Copyright
© 2023 The Voice Foundation. Published by Elsevier Inc. All rights reserved.
