Summary
Objective
To analyze the correlation between clinical and video laryngoscopy findings for 89
patients with bilateral vocal fold immobility (BVFI), unilateral vocal fold immobility
(UVFI), and healthy controls by quantitative analysis of normalized laryngeal outlet
(NLO), bowing index (BI), and supraglottic compression (SGC).
Methods
Laryngoscope pictures were taken by two reviewers, and all pictures were standardized
by scaling and calibrating to the same width and height in Image J. Three reviewers used quantitative measures to calculate BI, NLO, and SGC in Image J. We assessed reliability for each measurement by two-factor analysis of variance
(ANOVA) without replication to calculate the interclass correlation coefficient. Analysis
was broken down for each measurement in each group of interest by using a one-way
test. The total glottic area was obtained by calculating the normalized glottal gap
area from each image of maximum glottal closure during phonation.
Results
Overall reliability of all the measurements was 0.69 (IQ 0.58–0.83). Mean NLO from
UVFI, BVFI, and control groups differed significantly. There was no significant difference
between control and BVFI. The total glottic area did not consistently predict normalized
laryngeal outlet values. Mean normalized laryngeal outlet values of UVFI and BVFI
were significantly smaller in the BVFI groups compared with controls and UVFI. BI
values consistently predicted total glottic area in the BVFI group. Static SGC measurement
did not predict a difference between groups.
Conclusion
This is a reliable novel technique, which can be utilized in clinical settings. These
measurements have clinical relevance for managing voice disorders. NLO is the most
accurate measurement correlating with glottal incompetence. BI findings are sufficiently
specific to identify between UVFI and BVFI.
Key Words
To read this article in full you will need to make a payment
Purchase one-time access:
Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online accessOne-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:
Subscribe to Journal of VoiceAlready a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
REFERENCES
- Bilateral vocal fold immobility: clinical findings of ten cases and suggested treatment options.Auris Nasus Larynx. 2020; 47: 624-631https://doi.org/10.1016/j.anl.2020.02.005
- Vocal fold immobility: a longitudinal analysis of etiology over 20 years.Laryngoscope. 2007; 117: 1864-1870https://doi.org/10.1097/MLG.0b013e3180de4d49
- Changing etiology of vocal fold immobility.Laryngoscope. 1998; 108: 1346-1350https://doi.org/10.1097/00005537-199809000-00016
- Laryngeal neurophysiology and its clinical uses.Head Neck. 1996; 18: 78-86https://doi.org/10.1002/(SICI)1097-0347(199601/02)18:1<78::AID-HED10>3.0.CO;2-K
- A new stroboscopy rating form.J Voice. 1999; 13: 403-413https://doi.org/10.1016/S0892-1997(99)80045-9
- Influence of size and etiology of glottal gap in glottic incompetence dysphonia.Laryngoscope. 1998; 108: 514-518https://doi.org/10.1097/00005537-199804000-00010
- Quantitative videostroboscopic measurement of glottal gap and vocal function: an analysis of thyroplasty type I.Ann Otol Rhinol Laryngol. 1996; 105: 280-285https://doi.org/10.1177/000348949610500407
- Vocal fold atrophy: quantitative glottic measurement and vocal function.Ann Otol Rhinol Laryngol. 1997; 106: 544-551https://doi.org/10.1177/000348949710600702
- ImageJ2: imageJ for the next generation of scientific image data.BMC Bioinformatics. 2017; 18: 529https://doi.org/10.1186/s12859-017-1934-z
- The imageJ ecosystem: an open platform for biomedical image analysis.Mol Reprod Dev. 2015; 82: 518-529https://doi.org/10.1002/mrd.22489
- Quantitative analysis of videostroboscopic images in presbylarynges.Laryngoscope. 2001; 111: 2022-2027https://doi.org/10.1097/00005537-200111000-00029
- Influence of size and etiology of glottal gap in glottic incompetence dysphonia.Laryngoscope. 1998; 108: 514-518https://doi.org/10.1097/00005537-199804000-00010
- Histological changes in vocal fold growth and aging.Curr Opin Otolaryngol Head Neck Surg. 2014; 22: 460-465https://doi.org/10.1097/MOO.0000000000000108
- Histopathologic changes in the aging human cricoarytenoid joint.Laryngoscope. 1994; 104: 533-538https://doi.org/10.1002/lary.5541040505
- Dysphonia in the aging: physiology versus disease.Laryngoscope. 1992; 102: 139-144https://doi.org/10.1288/00005537-199202000-00007
- Association between voice handicap index and praat voice analysis in patients with benign vocal cord lesion before and after microscopic laryngeal surgery.Indian J Otolaryngol Head Neck Surg. 2019; 71: 482-488https://doi.org/10.1007/s12070-018-1363-y
- Correlation of VHI-30 to acoustic measurements across three common voice disorders.Journal of Voice. 2017; 31: 34-40https://doi.org/10.1016/j.jvoice.2016.02.016
- Glottic configuration after arytenoid adduction.Laryngoscope. 1994; 104: 965-969https://doi.org/10.1288/00005537-199408000-00010
Article info
Publication history
Published online: April 28, 2023
Accepted:
March 29,
2023
Publication stage
In Press Corrected ProofIdentification
Copyright
© 2023 The Voice Foundation. Published by Elsevier Inc. All rights reserved.