Research Article| Volume 3, ISSUE 4, P351-355, December 1989

Chronic dysphonia secondary to gastroesophageal reflux disease (GERD): Diagnosis using simultaneous dual-probe prolonged pH monitoring

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      The association of chronic dysphonia with gastroesophageal reflux has been reported in the otalaryngologic literature; unfortunately, these reports are primarily anecdotal. Because of the difficulty in documenting reflux, patients are often left without a definitive diagnosis or therapy. The purpose of this paper is to report on an objective method of documenting gastroesophageal reflux disease by using ambulatory esophageal and hypopharyngeal pH monitoring. 70% of the subjects who underwent simultaneous dual-probe pH monitoring evidenced reflux in the hypopharynx in both an upright and supine position. All of the subjects had erythema of the arytenoid cartilages on indirect examination; so this appears to be of clinical diagnostic significance.
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        • Olson NR
        The problem of gastroesophageal reflux.
        Otolaryngol Clin North Am. 1986; 19: 119-133
        • Ward P
        • Berci G
        Observations on the pathogenesis of chronic nonspecific pharyngitis and laryngitis.
        Laryngoscope. 1982; 92: 1377-1382
        • Ward PH
        • Zwitman D
        • Berci G
        Contact ulcers and granulomas of the larynx: new insight into their etiology as a basis for more rational treatment.
        Otolaryngol Head Neck Surg. 1980; 88: 262-269
        • Cherry J
        • Margulies SI
        Contact ulcer of the larynx.
        Laryngoscope. 1968; 78: 1937-1940
        • Goldberg M
        • Noyek A
        • Pritzker KPH
        Laryngeal granuloma secondary to gastroesophageal reflux.
        J Otolaryngol. 1978; 7: 196-202
        • Donnelly WH
        Histopathology of endotracheal intubation: an autopsy of 99 cases.
        Arch Pathol. 1969; 88: 511-520
        • Little FB
        • Koufman JA
        • Kohut RI
        • Marshall RB
        Effect of gastric acid on the pathogenesis of subglottic stenosis.
        Ann Otol Rhinol Laryngol. 1985; 94: 516-519
        • Delahunty JE
        • Ardran GM
        Globus hystericus: a manifestation of reflux esophagitis?.
        J Laryngol Otol. 1970; 84: 1049-1054
        • Weisskopf A
        Reflux esophagitis: a cause of globus.
        Otolaryngol Head Neck Surg. 1981; 89: 780-782
        • Glantz H
        • Kleinsasser O
        Chronic laryngitis and carcinoma.
        Arch Otol Rhinol Laryngol. 1960; 212: 349-357
        • Radigan LR
        • Glover JL
        • Shipley FE
        • et al.
        Barrett esophagus.
        Arch Surg. 1977; 112: 486-491
        • Smiley TB
        Cricopharyngeal complications of gastroesophageal reflux.
        in: Sorenson HR Jespon O Pederson SA The function of the esophagus. Odense University Press, Odense, Denmark1972: 725-731
        • Barish CF
        Respiratory complications of gastroesophageal reflux.
        Arch Intern Med. 1985; 145: 1882-1888
        • Lawrence V
        Do buzzards roost in your mouth at night?.
        NATS. 1983; (March/April): 19-42
        • O'Connor K
        Diagnosis and treatment of gastroesophageal reflux, or reflux revisited.
        Compr Ther. 1985; 11: 6-13
        • Johnson LF
        New concepts and methods in the study and treatment of gastroesophageal reflux disease.
        Med Clin North Am. 1981; 65: 195-222
        • Ward BW
        • Wu WC
        • Richter JE
        • Lui KW
        • Castell DO
        Ambulatory 24 hour esophageal pH monitoring. Technology searching for clinical application.
        J Clin Gastroenterol. 1986; 8: 59-67
        • Johnson LF
        • De Meester TR
        Twenty-four hour pH monitoring of the distal esophagus: a quantitative measure of gastroesophageal reflux.
        Am J Gastroenterol. 1974; 62: 325-332
        • Aronson AE
        Psychogenic voice disorders.
        in: Clinical voice disorders: an interdisciplinary approach. 2nd ed. Thieme, New York1985: 127-153
        • Delahunty JE
        • Cherry J
        Experimentally produced vocal cord granulomas.
        Laryngoscope. 1968; 78: 1941-1947
        • Preacher G
        Contact ulcer of the larynx: Part IV A clinical study of vocal re-reduction.
        J Speech Hear Disord. 1947; 12: 179-190.5
        • Cherry J
        • Margulies S
        Contact ulcer of the larynx.
        Laryngoscope. 1968; 78: 1937-1940
        • Ohman L
        • Tibbling L
        • Olafsson J
        • et al.
        Esophageal dysfunction with contact ulcer of the larynx.
        Ann Otol Rhinol Laryngol. 1983; 92: 228-230
        • Olson NR
        Effects of stomach acid on the larynx.
        in: Proc Am Laryngol Assoc. 104. 1983: 108-112
        • Feder RJ
        • Mitchell MJ
        Hyperfunctional, hyperacidic and intubation granulomas.
        Arch Otolaryngol. 1984; 110: 582-584
        • VonLeden H
        • Moore P
        The larynx and voice: laryngeal physiology under daily stress (Film).
        The Wm and Harriett Gould Foundation, Chicago1958
        • VonLeden H
        • Moore P
        Contact ulcers of the larynx.
        Arch Otolaryngol. 1960; 72: 746-752